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Article

Validation of a pXO2-A PCR assay to explore diversity among Italian isolates of Bacillus anthracis strains closely related to the live, attenuated Carbosap vaccine.

Journal of clinical microbiology - 1 Sept 2005

Muscillo M, La Rosa G, Sali M, De Carolis E, Adone R, Ciuchini F, Fasanella A

Abstract excerpt

Several circulating Bacillus anthracis strains isolated in Italy and belonging to the A1.a cluster, genotype 3 (A1.a-3) are genotypically indistinguishable from Carbosap, a live attenuated vaccine strain, containing both pXO1 and pXO2 plasmids. The genotype was assessed by using eight-locus multilocus variable-number tandem repeat analysis. We describe here the use of a ninth locus able to explore variability...

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Identifiers

PMID: 16145138
DOI: 10.1128/JCM.43.9.4758-4765.2005
PMCID: PMC1234070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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