Article
Molecular characterization of breast cancer cell lines by a low-density microarray.
International journal of oncology - 1 Oct 2005
de Longueville Francoise, Lacroix Marc, Barbuto Anna-Maria, Bertholet Vincent, Gallo Dominique, Larsimont Denis, Marcq Laurence, Zammatteo Nathalie, Boffe Sophie, Leclercq Guy, Remacle Jose
Abstract excerpt
We designed a low-density microarray carrying 132 DNA capture sequences highly specific for genes known to be differentially expressed among breast tumors and BCC lines or associated with specific tumor properties (cell-cycle alteration, proteolysis, adhesion, hormone sensitivity, etc). We analyzed gene expression in 11 BCC lines among which 6 had already been extensively studied (BT-474, Hs578T, MCF-7,...
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