Article
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma.
The British journal of dermatology - 1 Mar 2008
Asplund A, Gry Björklund M, Sundquist C, Strömberg S, Edlund K, Ostman A, Nilsson P, Pontén F, Lundeberg J
Abstract excerpt
BACKGROUND: Basal cell carcinomas (BCCs) are prevalent tumours with uniform histology that develop without any known precursor lesion. Alterations in the sonic hedgehog-patched1 signalling pathway are accepted as necessary events for tumorigenesis, and mutations in the patched1 gene are frequently present in tumours. OBJECTIVES: To analyse transcript profiles in BCC. METHODS: We used laser-assisted...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.