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Article

Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans.

Journal of medical genetics - 1 Sept 2005

Sun H, Ma Z, Li Y, Liu B, Li Z, Ding X, Gao Y, Ma W, Tang X, Li X, Shen Y

Abstract excerpt

BACKGROUND: Congenital or childhood cataract is clinically and genetically a highly heterogeneous lens disorder in children. Autosomal dominant inheritance is most common. OBJECTIVE: To report the identification of a mutation in the human CRYGS gene. SUBJECTS AND METHODS: A large six generation family affected by progressive polymorphic cortical cataract was investigated. After excluding loci for known cataract...

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Identifiers

PMID: 16141006
DOI: 10.1136/jmg.2004.028274
PMCID: PMC1736139

Genes

CRYGS

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