Article
Relationship between early HCV kinetics and T-cell reactivity in chronic hepatitis C genotype 1 during peginterferon and ribavirin therapy.
Journal of hepatology - 1 Nov 2005
Tang Kwok H, Herrmann Eva, Cooksley Helen, Tatman Nick, Chokshi Shilpa, Williams Roger, Zeuzem Stefan, Naoumov Nikolai V
Abstract excerpt
BACKGROUND/AIMS: To gain understanding of inter-individual differences of treatment response in hepatitis C virus genotype 1 (HCV-G1) patients, we investigated simultaneously the early HCV kinetics and virus-specific T-cell reactivity. METHODS: Thirty, treatment-naïve HCV-G1 patients received peginterferon-alfa2a 180 microg/week plus ribavirin 1000-1200 mg/day, with blood samples collected prospectively at...
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