Article
Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy.
Journal of hepatology - 1 Jul 2002
Rosen Hugo R, Ribeiro Ruy R, Weinberger Leor, Wolf Stephanie, Chung Minjun, Gretch David R, Perelson Alan S
Abstract excerpt
BACKGROUND/AIMS: The majority of patients with genotype 1 do not respond to interferon (IFN) plus ribavirin. Limited data exist on the use of induction followed by combination therapy. METHODS: In this prospective study of 28 patients infected with genotype 1, randomization involved either daily or twice daily high dose IFN for 6 weeks, followed by standard therapy of 3 million units three times a week in...
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