Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insights into the mutational history and prevalence of SCA1 in the Indian population through anchored polymorphisms.

Human genetics - 1 Oct 2005

Mittal Uma, Sharma Sangeeta, Chopra Rupali, Dheeraj Kalladka, Pal Pramod Kr, Srivastava Achal K, Mukerji Mitali

Abstract excerpt

There is a wide variation in prevalence of spinocerebellar ataxia type 1 (SCA1) in different populations. In the present study, we observed SCA1 in approximately 22% (37/167 families) of the autosomal dominant cerebellar ataxias (ADCAs) in the Indian population. We investigated the role of various genetic factors like repeat length, interruption pattern and chromosomal background in predisposing the repeats to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxin-1
Share to Ataxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Nuclear Proteins

Share to Primates

Share to Spinocerebellar Ataxias

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 16133185
DOI: 10.1007/s00439-005-0018-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insights into the mutational history and prevalence of SCA1 in the Indian population through anchored polymorphisms.PMID 16133185Read ↗

CAG repeat instability at SCA2 locus: anchoring CAA interruptions and linked single nucleotide polymorphisms.Semantic proximity Read ↗

Spinocerebellar ataxia type 27B (SCA27B) in India: insights from a large cohort study suggest ancient origin.Semantic proximity Read ↗

Genetic characterization of Spinocerebellar ataxia 1 in a South Indian cohort.Semantic proximity Read ↗

Pathogenic expansions of the SCA6 locus are associated with a common CACNA1A haplotype across the globe: founder effect or predisposing chromosome?Semantic proximity Read ↗

Identification and the origin of GAA expansion in FGF14 (Spinocerebellar Ataxia Type 27B): an insight from Indian subcontinent suggests an ancient originSemantic proximity Read ↗

Spinocerebellar ataxia 7 (SCA7) in Indian population: predilection of ATXN7-CAG expansion mutation in an ethnic population.Semantic proximity Read ↗

Extended haplotype with rs41524547-G defines the ancestral origin of SCA10.Semantic proximity Read ↗

Spinocerebellar ataxia type 2 has multiple ancestral origins.Semantic proximity Read ↗

Variation of CAG repeats and two intragenic polymorphisms at SCA3 locus among Machado-Joseph disease/SCA3 patients and diverse normal populations from eastern India.Semantic proximity Read ↗

Spinocerebellar ataxia type 2 has multiple ancestral originsSemantic proximity Read ↗

A novel haplotype of spinocerebellar ataxia type 6 contributes to the highest prevalence in western Japan.Semantic proximity Read ↗

Genetic and clinical profiles in a large cohort of Chinese individuals with spinocerebellar ataxia type 1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.