Article
Minor disturbances in central nervous system function in familial neurohypophysial diabetes insipidus.
Psychoneuroendocrinology - 1 Jan 2006
Bruins J, Kovács G L, Abbes A P, Burbach J P H, van den Akker E L T, Engel H, Franken A A M, de Wied D
Abstract excerpt
Familial neurohypophysial diabetes insipidus (FNDI) is caused by a defect in vasopressin synthesis and release as a result of a heterozygous mutation in the gene for the vasopressin prohormone. The predominant characteristic of FNDI is excessive thirst and urine production. However, vasopressin not only has peripheral endocrine effects, but also regulates numerous brain functions. We investigated whether central...
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