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Article

Targeted Identification of Glucocorticoid-attenuated Response Genes: <i>In Vitro</i> and <i>in Vivo</i> Models

1 Nov 2004

Abstract excerpt

Glucocorticoids attenuate the induction of numerous inflammatory mediators. We hypothesized that a targeted screening for genes with these regulatory characteristics, called glucocorticoid-attenuated response genes (GARGs), would be an efficient way to identify genes participating in glucocorticoid-sensitive inflammatory processes. An initial application of this idea, using an in vitro model, identified 12 cDNAs...

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PMID: 16113446
DOI: 10.1513/pats.200402-017ms

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