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Article

Neisseria meningitidis lactate permease is required for nasopharyngeal colonization.

Infection and immunity - 1 Sept 2005

Exley Rachel M, Goodwin Linda, Mowe Eva, Shaw Jonathan, Smith Harry, Read Robert C, Tang Christoph M

Abstract excerpt

Neisseria meningitidis is a human specific pathogen that is part of the normal nasopharyngeal flora. Little is known about the metabolic constraints on survival of the meningococcus during colonization of the upper airways. Here we show that glucose and lactate, both carbon energy sources for meningococcal growth, are present in millimolar concentrations within nasopharyngeal tissue. We used a mutant defective...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16113293
DOI: 10.1128/IAI.73.9.5762-5766.2005
PMCID: PMC1231078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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