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Article

De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero

19 Aug 2005

Abstract excerpt

OBJECTIVE: We describe a genetic basis for atrial fibrillation and short QT syndrome in utero. Heterologous expression of the mutant channel was used to define the physiological consequences of the mutation. METHODS: A baby girl was born at 38 weeks after induction of delivery that was prompted by bradycardia and irregular rythm. ECG revealed atrial fibrillation with slow ventricular response and short QT...

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Share to Cardiac Arrhythmias and Treatments
Share to Cardiac electrophysiology and arrhythmias
Share to Ion channel regulation and function

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Identifiers

PMID: 16109388
DOI: 10.1016/j.cardiores.2005.06.023

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