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REDUCED INFECTION AND PROTECTION FROM CLINICAL SIGNS OF CEREBRAL NEOSPOROSIS IN C57BL/6 MICE VACCINATED WITH RECOMBINANT MICRONEME ANTIGEN NCMIC1

1 Jun 2005

Abstract excerpt

NcMIC1 is a 460 amino acid Neospora caninum microneme protein implicated in host cell adhesion and invasion processes. In this study, we assessed the potential protectivity of NcMIC1-based vaccination against experimental N. caninum infection in mice, employing both recombinant antigen vaccines and DNA vaccines. Recombinant NcMIC1 (recNcMIC1) was expressed in Escherichia coli as gluthatione-S-transferase-fusion...

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PMID: 16108562
DOI: 10.1645/ge-401r

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