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IMMUNIZATION OF MICE WITH PLASMID DNA CODING FOR NcGRA7 OR NcsHSP33 CONFERS PARTIAL PROTECTION AGAINST VERTICAL TRANSMISSION OF NEOSPORA CANINUM

1 Jun 2003

Abstract excerpt

The purpose of the present study was to use direct plasmid deoxyribonucleic acid (DNA) injection to identify specific antigens that confer protection against congenital transfer of Neospora caninum. Inbred BALB/c mice were vaccinated before pregnancy with a recombinant plasmid containing sequences encoding N. caninum antigen NcGRA7 or NcsHSP33. The mice were challenged with N. caninum tachyzoites at 10-12 days of...

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PMID: 12880248
DOI: 10.1645/ge-2969

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