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Article

Shiga toxin-mediated hemolytic uremic syndrome: time to change the diagnostic paradigm?

PloS one - 10 Oct 2007

Bielaszewska Martina, Köck Robin, Friedrich Alexander W, von Eiff Christof, Zimmerhackl Lothar B, Karch Helge, Mellmann Alexander

Abstract excerpt

BACKGROUND: Hemolytic uremic syndrome (HUS) is caused by enterohemorrhagic Escherichia coli (EHEC) which possess genes encoding Shiga toxin (stx), the major virulence factor, and adhesin intimin (eae). However, the frequency of stx-negative/eae-positive E. coli in stools of HUS patients and the clinical significance of such strains are unknown. METHODOLOGY/PRINCIPAL FINDINGS: Between 1996 and 2006, we sought...

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Identifiers

PMID: 17925872
DOI: 10.1371/journal.pone.0001024
PMCID: PMC1995754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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