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Article

An isoform shift in the cardiac adenine nucleotide translocase expression alters the kinetic properties of the carrier in dilated cardiomyopathy.

European journal of heart failure - 1 Jan 2006

Dörner Andrea, Giessen Stefanie, Gaub Regina, Grosse Siestrup Helga, Schwimmbeck Peter L, Hetzer Roland, Poller Wolfgang, Schultheiss Heinz-Peter

Abstract excerpt

BACKGROUND: Impaired mitochondrial ADP/ATP transport and altered adenine nucleotide translocase (ANT) isoform expression characterized by enhanced ANT1 and decreased ANT2 expression have been implicated in the pathophysiology of dilated cardiomyopathy (DCM). It is still unknown whether restricted ANT function results from exogenous factors, or mutations in the ANT genes, or whether the imbalance in the isoform...

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Identifiers

PMID: 16107323
DOI: 10.1016/j.ejheart.2005.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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