Article
The myocardial expression of the adenine nucleotide translocator isoforms is specifically altered in dilated cardiomyopathy.
Herz - 1 May 2000
Dörner A, Schultheiss H P
Abstract excerpt
The adenine nucleotide translocator (ANT), the only mitochondrial carrier for ADP and ATP, combines mitochondrial energy-producing and cytosolic energy-consuming processes. The ANT function was observed to be impaired in explanted heart tissue from patients with dilated cardiomyopathy (DCM). In order to clarify whether an altered ANT isoform composition might be responsible for the restricted ANT function, we...
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