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Article

Age-related alterations to immune parameters in Labrador retriever dogs.

Veterinary immunology and immunopathology - 15 Dec 2005

Blount Daniel G, Pritchard David I, Heaton Paul R

Abstract excerpt

In order to assess age-related changes in the immune status of Labrador retriever dogs, leukocyte phenotypes, lymphocyte proliferative capacity, and serum antibody levels were measured in four cohorts of dogs, ranging from 2 to 10 years of age. Absolute numbers of white blood cells, lymphocytes, monocytes, granulocytes, and CD3+, CD4+, CD8+ and CD21+ lymphocytes significantly decreased with increasing age....

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Identifiers

PMID: 16105688
DOI: 10.1016/j.vetimm.2005.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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