Article
Unifying the spatial population dynamics and molecular evolution of epidemic rabies virus.
Proceedings of the National Academy of Sciences of the United States of America - 23 Aug 2005
Real Leslie A, Henderson J Caroline, Biek Roman, Snaman Jennifer, Jack Tracy Lambert, Childs James E, Stahl Eli, Waller Lance, Tinline Rowland, Nadin-Davis Susan
Abstract excerpt
Infectious disease emergence is under the simultaneous influence of both genetic and ecological factors. Yet, we lack a general framework for linking ecological dynamics of infectious disease with underlying molecular and evolutionary change. As a model, we illustrate the linkage between ecological and evolutionary dynamics in rabies virus during its epidemic expansion into eastern and southern Ontario. We...
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