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Variation in Interferon Sensitivity and Induction among Strains of Eastern Equine Encephalitis Virus

15 Aug 2005

Abstract excerpt

Eastern equine encephalitis virus (EEEV) causes human encephalitis in North America (NA), but in South America (SA) it has rarely been associated with human disease, suggesting that SA strains are less virulent. To evaluate the hypothesis that this virulence difference is due to a greater ability of NA strains to evade innate immunity, we compared replication of NA and SA strains in Vero cells pretreated with...

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PMID: 16103182
DOI: 10.1128/jvi.79.17.11300-11310.2005

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