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Article

Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA.

Journal of cellular biochemistry - 1 Oct 2005

Chang Yu-Wen E, Putzer Kevin, Ren Ling, Kaboord Barbara, Chance Terry W, Qoronfleh M Walid, Jakobi Rolf

Abstract excerpt

Cyclooxygenase 2 (COX-2) is an immediate early gene induced by a variety of stimuli and its expression is stimulated by individual activation of Ras or Rho GTPases. Here we investigate the role of coordinate activation of Ras and Rho GTPases in the induction of COX-2. Individual expression of con...

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Source

Identifiers

PMID: 16088958
DOI: 10.1002/jcb.20568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16088958-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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