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Article

TGF‐β control of cell proliferation

8 Aug 2005

Abstract excerpt

This article focuses on recent findings that the type V TGF-beta receptor (TbetaR-V), which co-expresses with other TGF-beta receptors (TbetaR-I, TbetaR-II, and TbetaR-III) in all normal cell types studied, is involved in growth inhibition by IGFBP-3 and TGF-beta and that TGF-beta activity is regulated by two distinct endocytic pathways (clathrin- and caveolar/lipid-raft-mediated). TGF-beta is a potent growth...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 16088940
DOI: 10.1002/jcb.20558

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