Article
Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma.
The Journal of pathology - 1 Oct 2005
Oue Naohide, Mitani Yoshitsugu, Aung Phyu Phyu, Sakakura Chouhei, Takeshima Yukio, Kaneko Mayumi, Noguchi Tsuyoshi, Nakayama Hirofumi, Yasui Wataru
Abstract excerpt
Regenerating islet-derived family, member 4 (Reg IV) is a candidate marker for cancer and inflammatory bowel disease. In the present study, immunohistochemical analysis of Reg IV was performed in various human neoplastic (n = 289) and non-neoplastic tissues. In the stomach, foveolar epithelium was negative for Reg IV, whereas goblet cells of intestinal metaplasia and neuroendocrine cells at the base of intestinal...
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