Article
Failure to find association between TRAR4 and schizophrenia in the Chinese Han population.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2006
Duan S, Du J, Xu Y, Xing Q, Wang H, Wu S, Chen Q, Li X, Li X, Shen J, Feng G, He L
Abstract excerpt
The TRAR4 gene locates in SCZD5 (MIM 603175), which a number of studies have linked with schizophrenia. One recent study suggested that three TRAR4 variants (M1: rs4305745, P=0.0014; M2: rs6903874, P=0.0026; M3: rs6937506, P=0.0052) in the 3'-UTR were associated with schizophrenia. To replicate these findings, we conducted a family-based association study within a sample of 235 Chinese Han trios. However, we...
Read the complete abstract on PubMed