Article
[Significance of polymorphisms in variable number of tandem repeat region of interleukin-4 gene in recurrence of childhood steroid sensitive nephrotic syndrome].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Jun 2005
Liu Hai-mei, Shen Qian, Xu Hong, Yang Yi
Abstract excerpt
OBJECTIVE: Recent studies suggest that T cell dysfunction, especially IL-4, may be involved in the pathogenesis of steroid sensitive nephrotic syndrome (SSNS). The aim of this study was to investigate the association between the polymorphisms in variable numbers of tandem repeat region (VTR) of IL-4 gene and childhood SSNS. METHOD: The polymorphism in the IL-4 gene was identified by using the polymerase chain...
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