Article
Differential expression of genes at stages when regeneration can and cannot occur after injury to immature mammalian spinal cord.
Cellular and molecular neurobiology - 1 Mar 2005
Mladinic Miranda, Wintzer Marie, Del Bel Elaine, Casseler Cristina, Lazarevic Dejan, Crovella Sergio, Gustincich Stefano, Cattaneo Antonino, Nicholls John
Abstract excerpt
Comprehensive screens were made for genes that change their expression during a brief critical period in development when neonatal mammalian central nervous system (CNS) loses its capacity to regenerate. In newly born opossums older than 12 days regeneration ceases to occur in the cervical spinal cord. It continues for 5 more days in lumbar regions. The mRNA's expressed in cords that do and do not regenerate were...
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