Article
Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis.
American journal of respiratory and critical care medicine - 15 Oct 2005
Saiman Lisa, Mayer-Hamblett Nicole, Campbell Preston, Marshall Bruce C
Abstract excerpt
RATIONALE: We recently reported a randomized, placebo-controlled trial of azithromycin in patients with cystic fibrosis (CF) that demonstrated a 6.2% improvement in the 168-d relative change in FEV1 among azithromycin participants compared with placebo participants. OBJECTIVES: In the current analyses, heterogeneity of treatment response and the association between FEV1 and the risk of pulmonary exacerbations...
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