Long- versus short-duration systemic corticosteroid regimens for acute exacerbations of COPD: A systematic review and meta-analysis of randomized trials and cohort studies

Abstract excerpt

While systemic corticosteroids quicken patient recovery during acute exacerbations of COPD, they also have many adverse effects. The optimal duration of corticosteroid administration remains uncertain. We performed a systematic review and meta-analysis to compare patient outcomes between short-(≤7 day) and long- (>7 day) corticosteroid regimens in adults with acute exacerbations of COPD. MEDLINE, EMBASE, CENTRAL,...

Topics

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• Adrenal Cortex Hormones
• Adrenergic beta-2 Receptor Agonists
• Androstadienes
• Bronchodilator Agents
• Double-Blind Method
• Muscarinic Antagonists
• Practice Guidelines as Topic
• Pulmonary Disease, Chronic Obstructive

Identifiers and source

Literature Corpus work

d469aa09-76db-5634-a0e6-11e81ea3e662

DOI

10.1101/2023.09.12.23295446