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Article

Age dependent penetrance of three different superoxide dismutase 1 (sod 1) mutations.

The International journal of neuroscience - 1 Aug 2005

Aggarwal Arun, Nicholson Garth

Abstract excerpt

The age of onset of motor neuron disease in Cu/Zn superoxide dismutase 1 (SOD1) mutation carriers are variable, commencing at any time from the second decade. The authors performed a retrospective analysis of family information in pedigrees dating back to the 1780s, to determine the age-dependent penetrance of three different SOD1 mutations: Glu100Gly, Ile113Thr, and Val148G1y. The penetrance of symptomatic MND...

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Source

Identifiers

PMID: 16040355
DOI: 10.1080/00207450590914392

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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