Article
Effect of antibiotic sub inhibitory concentration on cytolethal distending toxin production by Campylobacter jejuni.
The Journal of infection - 1 Aug 2005
Ismaeel Abdulrahman Y, Senok Abiola C, Bindayna Khalid M, Bakhiet Moiz, Al Mahmeed Ali, Yousif Ahmed Q, Botta Giuseppe A
Abstract excerpt
OBJECTIVES: To investigate the effect of pre-exposure antibiotics on cytolethal distending toxin (CDT) production and toxigenic effect of C. jejuni. METHODS: Sonicates and filtrates were prepared from known cdt+ and cdt- isolates of C. jejuni which had been pre-exposed to varying concentrations (MIC, 1/2 MIC, 1/4 MIC, 1/8 MIC) of erythromycin and ciprofloxacin. The CDT toxigenic effect was examined using INT 407...
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