Article
The recombinant HLA-B*5518 allele supports the evidence of conserved haplotype association of rare alleles.
Tissue antigens - 1 Aug 2005
Lebedeva T V, Huang A, Ohashi M, Sibilia P, Alosco S M, Kempenich J, Yu N
Abstract excerpt
Allelic polymorphism of the major histocompatibility complex arises mostly from gene recombination. Intralocus gene recombination usually involves short fragments of DNA leading most commonly to single-nucleotide substitutions and rarely involves large fragments. Here, we report a new recombinant human leukocyte antigen (HLA)-B*5518 allele that has arisen via recombination of a large fragment of DNA spanning more...
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