Article
Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair.
Nature structural & molecular biology - 1 Aug 2005
Panigrahi Gagan B, Lau Rachel, Montgomery S Erin, Leonard Michelle R, Pearson Christopher E
Abstract excerpt
Expansion of (CTG)*(CAG) repeats, the cause of 14 or more diseases, is presumed to arise through escaped repair of slipped DNAs. We report the fidelity of slipped-DNA repair using human cell extracts and DNAs with slip-outs of (CAG)(20) or (CTG)(20). Three outcomes occurred: correct repair, escap...
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