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Article

Divalent cation modulation of a-type potassium channels in acutely dissociated central neurons from wide-type and mutant Drosophila.

Journal of neurogenetics - 1 Jan 2000

Xu Tai-Xiang, Gong Neng, Xu Tian-Le

Abstract excerpt

Drosophila mutants provide an ideal model to study channel-type specificity of ion channel regulation in situ. In this study, the effects of divalent cations on voltage-gated K+ currents were investigated in acutely dissociated central neurons of Drosophila third instar larvae using the whole-cell patch-clamp recording. Our data showed that micromolar Cd2+ enhanced the peak inactivating current (I(A)) without...

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PMID: 16024441
DOI: 10.1080/01677060591007182

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