Article
The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects.
European journal of clinical pharmacology - 1 Aug 2005
Bramness Jørgen G, Skurtveit Svetlana, Gulliksen Margaretha, Breilid Harald, Steen Vidar M, Mørland Jørg
Abstract excerpt
AIMS: The aim of the present study was to investigate if subjects with one normal and one non-functional CYP2C19 allele (intermediate metabolizers; IMs) metabolized carisoprodol differently than individuals with two normal CYP2C19 alleles (extensive metabolizers; EMs) We also wanted to investigat...
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