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Article

The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects.

European journal of clinical pharmacology - 1 Aug 2005

Bramness Jørgen G, Skurtveit Svetlana, Gulliksen Margaretha, Breilid Harald, Steen Vidar M, Mørland Jørg

Abstract excerpt

AIMS: The aim of the present study was to investigate if subjects with one normal and one non-functional CYP2C19 allele (intermediate metabolizers; IMs) metabolized carisoprodol differently than individuals with two normal CYP2C19 alleles (extensive metabolizers; EMs) We also wanted to investigate whether the use of oral contraceptives influences the metabolism of carisoprodol in EMs and IMs. Impairing effects on...

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Identifiers

PMID: 16021435
DOI: 10.1007/s00228-005-0970-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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