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Comparative analysis of development-related gene expression in mouse preimplantation embryos with different developmental potential

1 Jan 2005

Abstract excerpt

The potential of embryonic and somatic cell nuclear-transferred (NT) mouse oocytes to develop into young is low compared with bovine NT oocytes. To examine the reasons for the low developmental potential of NT mouse oocytes, we analyzed the gene expression patterns of six development-related genes (Oct4, Nanog, Stat3, stella, FGF4, and Sox2) during preimplantation development in manipulated oocytes with different...

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PMID: 16013066
DOI: 10.1002/mrd.20346

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