Article
Novel markers of the human follicle-associated epithelium identified by genomic profiling and microdissection.
Gastroenterology - 1 Jul 2005
Anderle Pascale, Rumbo Martin, Sierro Frédéric, Mansourian Robert, Michetti Pierre, Roberts Matthew A, Kraehenbuhl Jean-Pierre
Abstract excerpt
BACKGROUND & AIMS: Regulation of gene expression in the follicle-associated epithelium (FAE) over Peyer's patches is largely unknown. CCL20, a chemokine that recruits immature dendritic cells, is one of the few FAE-specific markers described so far. Lymphotoxin beta (LTalpha1beta2) expressed on the membrane of immune cells triggers CCL20 expression in enterocytes. In this study, we measured expression profiles of...
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