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Article

In vitro inhibition of R5 HIV-1 infectivity by X4 V3-derived synthetic peptides.

International journal of molecular medicine - 1 Aug 2005

Baritaki Stavroula, Dittmar Matthias T, Spandidos Demetrios A, Krambovitis Elias

Abstract excerpt

The aim of the present study was to investigate the inhibitory effect of synthetic peptides derived from the principle neutralizing domain of the V3 loop of the HIV-1 gp120 in the infectivity rates of HIV-1 variants with different tropism. Assessment of the viral infectivity was determined by detection of soluble HIV p24gag antigen in the culture supernatants of PM-1 T cells and primary macrophages after in vitro...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16012771

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vitro inhibition of R5 HIV-1 infectivity by X4 V3-derived synthetic peptides.PMID 16012771Read ↗

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Effect of mutations in the V3 loop of HIV-1 gp120 on infectivity and susceptibility to proteolytic cleavage.Semantic proximity Read ↗

Phospholipid interactions of synthetic peptides representing the N-terminus of HIV gp41Semantic proximity Read ↗

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