Article
The Ala54Thr polymorphism of the fatty acid-binding protein 2 gene is associated with a change in insulin sensitivity after a change in the type of dietary fat.
The American journal of clinical nutrition - 1 Jul 2005
Marín Carmen, Pérez-Jiménez Francisco, Gómez Purificación, Delgado Javier, Paniagua Juan Antonio, Lozano Aquiles, Cortés Begoña, Jiménez-Gómez Yolanda, Gómez María José, López-Miranda José
Abstract excerpt
BACKGROUND: Insulin resistance, a condition associated with type 2 diabetes, results from the interaction of environmental and genetic factors. OBJECTIVE: We examined the influence of the intestinal fatty acid-binding protein 2 (FABP2) Ala54Thr polymorphism on insulin sensitivity. DESIGN: Fifty-nine healthy young subjects (28 were Ala54/Ala54, 27 were Ala54/Thr54, and 4 were Thr54/Thr54) completed 3 diets, each...
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