Article
Influence of ALA54THR polymorphism of fatty acid binding protein 2 on lifestyle modification response in obese subjects.
Annals of nutrition & metabolism - 1 Jan 2006
de Luis D A, Aller R, Izaola O, Sagrado M Gonzalez, Conde R
Abstract excerpt
BACKGROUND/AIM: It has been found that the expression of fatty acid binding protein 2 (FABP2) mRNA is under dietary control. A G-to-A transition at codon 54 of FABP2 results in an amino acid substitution (from Ala 54 to Thr 54). This polymorphism was associated with high insulin resistance and high fasting insulin concentrations. The aim of our study was to investigate the influence of Thr54 polymorphism in the...
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