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Article

The RsaI polymorphism in the estrogen receptor-beta gene is associated with male infertility.

The Journal of clinical endocrinology and metabolism - 1 Sept 2005

Aschim Elin L, Giwercman Aleksander, Ståhl Olof, Eberhard Jakob, Cwikiel Magdalena, Nordenskjöld Agneta, Haugen Trine B, Grotmol Tom, Giwercman Yvonne L

Abstract excerpt

CONTEXT: Hypospadias, cryptorchidism, testicular cancer, and low semen quality have been proposed as being parts of the testicular dysgenesis syndrome (TDS) hypothetically due to changes in the androgen-estrogen balance in utero. Estrogens and estrogen receptors (ERs) play a role in regulating testicular function. ERbeta contains two silent polymorphisms, RsaI (G1082A) and AluI (G1730A). OBJECTIVE: We...

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Identifiers

PMID: 15998774
DOI: 10.1210/jc.2005-0263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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