Article
"A gene for...": the nature of gene action in psychiatric disorders.
The American journal of psychiatry - 1 Jul 2005
Kendler Kenneth S
Abstract excerpt
A central phrase in the new "GeneTalk" is "X is a gene for Y," in which X is a particular gene on the human genome and Y is a complex human disorder or trait. This article begins by sketching the historical origins of this phrase and the concept of the gene-phenotype relationship that underlies it. Five criteria are then proposed to evaluate the appropriateness of the "X is a gene for Y" concept: 1) strength of...
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