Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent.

doi:10.1016/j.ygyno.2005.05.022

Article

Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent.

Gynecologic oncology - 1 Sept 2005

Barnes Mack N, Chhieng David F, Dreher Mackenzie, Jones Jennifer L, Grizzle William E, Jones Laura, Talley Lynya, Partridge Edward E

Abstract excerpt

BACKGROUND: A pilot study was undertaken to determine the feasibility of examining a COX-2 inhibitor (Celecoxib) as a chemopreventive agent in women at increased risk of ovarian cancer undergoing risk reducing salpingoophorectomy. METHODS: Women at elevated inherited risk of ovarian carcinoma pursuing risk reducing salpingoophorectomy were eligible for this trial. Ten patients were assigned to a control group...

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