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Article

5alpha-Reductase activity in Lycopersicon esculentum: cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes.

The Journal of steroid biochemistry and molecular biology - 1 Aug 2005

Rosati Fabiana, Bardazzi Irene, De Blasi Paola, Simi Lisa, Scarpi Dina, Guarna Antonio, Serio Mario, Racchi Milvia L, Danza Giovanna

Abstract excerpt

The full-length cDNA (LeDET2) encoding a 257 amino acid protein homolog of Arabidopsis DET2 (AtDET2) was isolated in tomato (Lycopersicon esculentum). LeDET2 has 76% similarity with AtDET2 and structural characteristics conserved among plant and mammalian steroid 5alpha-reductases (5alphaRs). LeDET2 is ubiquitously expressed in tomato tissues with higher levels in leaf than in stem, root, seed and callus. When...

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PMID: 15993049
DOI: 10.1016/j.jsbmb.2005.04.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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