Article
Conservation of function between mammalian and plant steroid 5alpha-reductases.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1997
Li J, Biswas M G, Chao A, Russell D W, Chory J
Abstract excerpt
Arabidopsis det2 mutants are small dark-green dwarfs displaying pleiotropic defects in light-regulated development during multiple stages of the plant life cycle. The DET2 gene encodes a protein that shares approximately 40% sequence identity with mammalian steroid 5alpha-reductases and is implicated in the synthesis of a class of plant steroids, the brassinosteroids. Here we show that the DET2 protein, when...
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