Article
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion.
Thrombosis research - 1 Jan 2006
Kim Nam Keun, Choi Yoon Kyung, Kang Myung Seo, Choi Dong Hee, Cha Sun Hee, An Myung Ok, Lee Suman, Jeung Mingull, Ko Jung Jae, Oh Doyeun
Abstract excerpt
OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR) mutations known to be associated with hyperhomocysteinemia may be a risk factor for recurrent spontaneous abortion. Recently 28-bp tandem repeat polymorphism in thymidylate synthase enhancer region (TSER) was reported to affect plasma homocysteine level. We investigated the association between plasma homocysteine level and MTHFR and TSER genotypes. METHODS:...
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