Article
Transcriptional regulation of beta-defensin-2 by lipopolysaccharide in cultured human cervical carcinoma (HeLa) cells.
FEMS immunology and medical microbiology - 1 Jul 2005
Mineshiba Junji, Myokai Fumio, Mineshiba Fumi, Matsuura Kaori, Nishimura Fusanori, Takashiba Shogo
Abstract excerpt
Human beta-defensin-2 (hBD-2) is an antimicrobial peptide with a broad spectrum of antimicrobial activity against bacteria, yeast and fungi. Here, we analyzed the transcriptional regulation of hBD-2 in cultured human cervical carcinoma (HeLa) cells with or without lipopolysaccharide (LPS). DNA from position -329 to -39 in the hBD-2 promoter region contained the consensus binding sites for transcription factors,...
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