Worldwide Disseminated <i>armA</i> Aminoglycoside Resistance Methylase Gene Is Borne by Composite Transposon Tn <i>1548</i>

Abstract excerpt

The armA (aminoglycoside resistance methylase) gene, which confers resistance to 4,6-disubstituted deoxystreptamines and fortimicin, was initially found in Klebsiella pneumoniae BM4536 on IncL/M plasmid pIP1204 of ca. 90 kb which also encodes the extended-spectrum beta-lactamase CTX-M-3. Thirty-four enterobacteria from various countries that were likely to produce a CTX-M enzyme since they were more resistant to...

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