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Widespread occurrence of aminoglycoside resistance due to ArmA methylase in imipenem-resistant Acinetobacter baumannii isolates in China

8 Jun 2007

Abstract excerpt

Sir, Imipenem-resistant Acinetobacter baumannii (IRAB) infections and nosocomial outbreaks have been reported in many countries. Epidemic strains of IRAB are often resistant to many other antimicrobial agents, including aminoglycosides. One of the most important mechanisms of aminoglycoside resistance is post-transcriptional rRNA methylation by 16S rRNA methylases. The first 16S rRNA methylase gene, rmtA, was...

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PMID: 17561497
DOI: 10.1093/jac/dkm208

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