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Article

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

23 Jun 2005

Abstract excerpt

Multiple sclerosis afflicts more than 1 million individuals worldwide and is widely considered to be an autoimmune disease. Traditionally, CD4(+) T helper cells have almost exclusively been held responsible for its immunopathogenesis, partly because certain MHC class II alleles clearly predispose for developing multiple sclerosis and also, because of their importance in inducing experimental autoimmune...

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PMID: 15975943
DOI: 10.1093/brain/awh578

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