Article
Helicobacter pylori -Induced IL-8 Production by Gastric Epithelial Cells Up-Regulates CD74 Expression
1 Jul 2005
Abstract excerpt
CD74, or the class II MHC-associated invariant chain, is best known for the regulation of Ag presentation. However, recent studies have suggested other important roles for this protein in inflammation and cancer studies. We have shown that CD74 is expressed on the surface of gastric cells, and Helicobacter pylori can use this receptor as a point of attachment to gastric epithelial cells, which lead to IL-8...
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