Article
Impact of Mating Type, Serotype, and Ploidy on the Virulence of <i>Cryptococcus neoformans</i>
22 Apr 2008
Abstract excerpt
Hybridization with polyploidization is a significant biological force driving evolution. The effect of combining two distinct genomes in one organism on the virulence potential of pathogenic fungi is not clear. Cryptococcus neoformans, the most common cause of fungal infection of the central nervous system, has a bipolar mating system with a and alpha mating types and occurs as A (haploid), D (haploid), and AD...
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